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Department of Biomedical Engineering

Cho, Cheul H.

Contact Info
Title: Assistant Research Professor
Email: cho@njit.edu
Office: 204 York Center
Phone: 973-596-5381
Dept: Biomedical Engineering
Webpage: http://web.njit.edu/~cho

About Dr. Cho



Education

 

Postdoctoral Fellow, Harvard Medical School, Boston, MA
Ph.D. Chemical Engineering, Wayne State University, Detroit, MI
M.S. Biomedical Engineering, University of Iowa, Iowa City, IA
B.S. Chemical Engineering, Dong-A University, Busan, South Korea

Professional Experience

Assistant Research Professor, Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, 2014-present

Assistant Professor, Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, 2007-2014

Adjunct Assistant Professor, Department of Cell Biology and Molecular Medicine, University of Medicine and Dentistry of New Jersey (UMDNJ) - New Jersey Medical School, Newark, NJ, 2008-present

Research Fellow, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2003-2007

Research Assistant, Department of Chemical Engineering, Wayne State University, Detroit, Michigan, 1999-2003

Research Scientist, Biomedical Research Center, Korea Institute of Science & Technology (KIST), Seoul, Korea, 1997-1998

Computer Administrator, Ministry of National Defense, Security Agency, Seoul, South Korea, 1994-1996 (served military duty)

Research Assistant, Department of Biomedical Engineering, University of Iowa, Iowa City, IA, 1991-1993

 

Professional Activities/Organizations

 

BMES (Biomedical Engineering Society), Member
AIChE (American Institute of Chemical Engineer), Member
ISSCR (International Society for Stem Cell Research), Member

 

Reviewer for Journals 

Acta Biomaterialia
ACS Book Chapter
Biomedical Materials
Biomedical Microdevices
Biotechnology Progress
Critical Reviews in Biomedical Engineering
FASEB Journal
Journal of Biomedical Materials Research
Journal of Tissue Engineering and Regenerative Medicine 
PlosOne
Tissue Engineering

Courses Taught

 

Biological and Chemical Foundations of Biomedical Engineering
Cell and Biomaterial Engineering Laboratory
Research Skills in Stem Cell Tissue Engineering

Research Interests

 

Stem Cell Bioengineering and Regenerative Medicine
Multi-lineage Differentiation of Embryonic Stem Cells
Engineering 3-D Tissue Construct for Tissue Repair
In Vitro Co-Culture Models for Cell-Cell Interactions
Cell-Cell, Cell-ECM, Cell-Biomaterial Interactions
Cellular and Tissue Engineering (Liver, Cardiac, Neural)
Micropatterning of Cells and ECM for Cellular Interactions
Scaffold Tissue Engineering
Polymeric Biomaterials Design and Characterization
Liver Tissue Regeneration (In Vitro and In Vivo Models)

 

Research Opportunities

We welcome your interest and inquiries about Stem Cells and Tissue Engineering Lab. Research opportunities are available to students who are highly motivated and interested in doing research in the area of stem cell bioengineering, tissue engineering, and polymeric biomaterials. If you are interested in doing research in my lab, please contact me.


Selected Publications

 

Nolan Skop, Frances Calderon, Cheul H. Cho, Chirag Gandhi, Steven Levison, “Improvements in Biomaterial Matrices for Neural Precursor Cell Transplantation”, Molecular and Cellular Therapies, Vol. 2:19, 2014
Anil Shrirao, Frank Kung, Derek Yip, Cheul H. Cho, Ellen Townes-Anderson, “Vacuum-assisted Fluid Flow in Microchannels to Pattern Substrates and Cells for Cell Biological Studies”, Biofabrication, Vol. 6, 035016 (13pp), 2014
Derek Yip, Cheul H. Cho, “A Multicellular 3D Heterospheroid Model of Liver Tumor and Stromal Cells in Collagen Gel for Anti-Cancer Drug Testing”, Biochemical and Biophysical Research Communications, Vol. 433 (3):327-332, 2013
Nolan Skop, Frances Calderon, Steven Levison, Chirag Gandhi, Cheul H. Cho, “Heparin Cross-Linked Chitosan Microspheres for the Delivery of Neural Stem Cells and Growth Factors for Central Nervous System Repair”, Acta Biomaterialia, Vol. 9 (6): 6834-6843, 2013
Ali Hussain, George Collins, Derek Yip, Cheul H. Cho, “Functional 3D Cardiac Co-Culture Model Using Bioactive ChitosanNanofiber Scaffolds”, Biotechnology and Bioengineering, Vol. 110 (2); 637-647, 2013 [Cover Feature] [Highlighted in Extracellular Matrix News 3.37]
Nolan Skop, Frances Calderon, Cheul H. Cho, Chirag Gandhi, Steven Levison, “Optimizing a Multifunctional Microsphere Scaffold to Improve Neural Stem Cell Transplantation for Traumatic Brain Injury Repair”, Journal of Tissue Engineering and Regenerative Medicine, Published online: 9 OCT 2013 (DOI: 10.1002/term.1832), 2013           
Anil B. Shrirao, Ali Hussain, Cheul H. Cho, and Raquel Perez-Castillejos, “Adhesive-Tape Soft Lithography for Patterning Mammalian Cells: Application To Wound-Healing Assays”, BioTechniques, Vol. 53 (5): 315–318, 2012
Young-Dong Yu, Ki-Hun Kim, Sung-Gyu Lee, Sang-Yong Choi, Young-Chul Kim, Kwan-Su, Byun, In-Ho Cha,Kye-Yoon Park, Cheul-Hyung Cho, Dong-Ho Choi, Hepatic Differentiation from Human Embryonic Stem Cells Using Stromal Cells, Journal of Surgical Research, Oct;170(2):e253-61, 2011
Cho, C. H., Park, J., Tilles, A., Berthiaume, F., Toner, M., Yarmush, M. Cell Layering of Patterned Co-Cultures Using Microfabricated Elastomeric Stencils, BioTechniques Protocol,2011
Cho, C. H., Park, J., Tilles, A., Berthiaume, F., Toner, M., Yarmush, M. Layered Patterning of Hepatocytes in Co-Culture Systems Using Microfabricated Stencils. BioTechniques,Jan;48: 47-52, 2010
Cheul H. Cho, Francois Berthiaume, Arno Tilles, Martin Yarmush, “A New Technique for Primary Hepatocyte Expansion In Vitro”, Biotechnology and Bioengineering, 101; 345-356, 2008
Daan van Poll, Biju Parekkadan, Cheul H. Cho, François Berthiaume, Arno W. Tilles, Yaakov Nahmias, Martin L. Yarmush, Mesenchymal Stem Cell-Derived Molecules Directly Modulate Hepatocellular Death and Regeneration In Vitro and In Vivo, Hepatology, May;47(5): 1634-43, 2008
Natesh Parashurama, Koby Nahmias, Cheul H. Cho, Daan Poll, Arno W. Tilles, Francois Berthiaume, and Martin L. Yarmush, “Activin alters the kinetics of endoderm induction and in vivo differentiation in collagen gel cultures of embryonic stem cells”, Stem Cells, Feb; 26(2): 474-84, 2008 (peer)
Cheul H. Cho, Natesh Parashurama, Eric Y.H. Park, Kazuhiro Suganuma, Yaakov Nahmias, Jaesung Park, Arno W. Tilles, Francois Berthiaume, and Martin L. Yarmush, “Homogenous Differentiation of Hepatocyte-like Cells from Embryonic Stem Cells: Applications for the Treatment of Liver Failure, FASEB Journal, March;22(3):898-909, 2008 (peer)
Cheul H. Cho, James F. Eliason and Howard WT Matthew, “Application of Porous Glycosaminoglycan-Based Scaffolds for Expansion of Human Cord Blood Stem Cells in Perfusion Culture, Journal of Biomedical Materials Research Part A, 86A: 98-107, 2008
Jae-Sung Park, Cheul H. Cho, Natesh Parashurama, Yawen Li, Francois Berthiaume, Arno Tilles, Mehmet Toner, Martin Yarmush, “Microfabrication-based Modulation of Embryonic Stem Cell Differentiation, Lab on a Chip, 7, 1018-1028, 2007
Cheul H. Cho, Jaesung Park, Francois Berthiaume, Arno Tilles, Mehmet Toner, Martin Yarmush, “Oxygen Uptake Rates and Liver-Specific Functions of Hepatocyte and 3T3 Fibroblast Co-Cultures”, Biotechnology and Bioengineering, 97 (1); 188-199, 2007[Cover Feature]
C.H. Cho, J.B. Choi, K. Choi, "Finite Element Analysis for the Contact Stress of Ultra-High Molecular Weight Polyethylenein Total Knee Arthroplasty”, Journal of Korean Society of Medical and Biological Engineering,Vol.20. No.1, pp.37-44, 1999
Y.K. Cho, C.H. Cho, J.B. Choi, T.S. Lee, K. Choi, "A Numerical Study on the Response of the Tibial Component in Total Knee Arthroplasty to Longitudinal Impact”, Journal of Korean Society of Medical and Biological Engineering,Vol.19. No.5, pp.503-510, 1998
M.J. Vonesh, C.H. Cho, J.V. Pinto, B.J. Kane, D.S. Lee, S.I. Roth, K.B. Chandran, D.D. McPherson, "Regional Vascular Mechanical Properties by 3-D Intravascular Ultrasound with Finite Element Analysis", American Journal of Physiology, 272 (Heart Circ. Physiol. 41): H425-H437, 1997

SCI Impact Factors for Journals (2005 Thomson Scientific)

  • Hepatology (9.8), FASEB Journal (7.1), Stem Cells (6.1), Lab on a Chip (5.3), Biotechnology and Bioengineering (2.5), Journal of Biomedical Materials Research A (2.5), Tissue Engineering (2.9), American Journal of Physiology (3.6), BioTechniques (2.3)

 

Conference Abstracts /Presentations (Selected)

  • Cheul H. Cho, Natesh Parashurama, Eric Y.H. Park, Kazuhiro Suganuma, Yaakov Nahmias, Jaesung Park, Arno W. Tilles, Francois Berthiaume, and Martin L. Yarmush, “Directed Differentiation of Embryonic Stem Cells into Functional Hepatocyte-Like Cells: Applications for the Treatment of Liver Failure”, 2008 Annual Meeting of International Society for Stem Cell Research (ISSCR) Philadelphia, PA, June 11-14, 2008
  • Natesh Parashurama, Koby Nahmias, Cheul H. Cho, Daan Poll, Arno W. Tilles, Francois Berthiaume, and Martin L. Yarmush, “Activin alters the kinetics of endoderm induction and in vivo differentiation in collagen gel cultures of embryonic stem cells”, 2008 SBE’s International Conference on Stem Cell Engineering, Coronado, CA, Jan 20-23, 2008
  • Eric Y.H. Park, Cheul H. Cho, Arno W. Tilles, Martin L.Yarmush, “Engineering a stem cell niche to differentiate embryonic stem cells into functional hepatocytes”, 2007 Annual Meeting of Biomedical Engineering Society (BMES), Los Angeles, CA, 2007
  • Deepak Nagrath, Eric Y.H. Park, Cheul H. Cho, Marco Elchiver, Rongjun Zuo, Francois Berthiaume, Arno W. Tilles, Martin L.Yarmush.Maturation of Embyronic Stem Cells Into Hepatocytes Using Metabolic Flux Analysis, 2007 Annual Meeting of Biomedical Engineering Society (BMES), Los Angeles, CA, 2007
  • Eric Y.H. Park, Cheul H. Cho, Arno Tilles, Martin Yarmush, Derivation of Functional Hepatocytes from Murine Embryonic Stem Cells, Keystone Symposia, Tissue Engineering and Development Biology, Snowbird, Utah, April 12 - 17, 2007
  • Cheul H. Cho, Natesh Parashurama, Arno W. Tilles, Francois Berthiaume, and Martin L. Yarmush, Embryonic Stem Cell Differentiation into Early Endodermal and Hepatic Lineage Cells, 2006 Annual Methods in Bioengineering Conference, Cambridge, MA, July 17-18, 2006
  • Cheul H. Cho, Natesh Parashurama, Arno Tilles, Francois Berthiaume, Martin Yarmush, Embryonic Stem Cell Differentiation into Early Endodermal and Hepatic Lineage Cells, Second Annual Tony & Shelly Malkin Stem Cell Symposium, Harvard Club of Boston, MA, December 2, 2005
  • Cheul H. Cho, Natesh Parashurama, Arno Tilles, Francois Berthiaume, Martin Yarmush, Induction of Embryonic Stem Cells into Endoderm Hepatic Lineage Cells, 2005 Annual Meeting of AIChE (American Institute of Chemical Engineerers), Bioengineering Division, Cincinnati, OH, November, 2005
  • Cheul H. Cho, Jae-Sung Park, Francois Berthiaume, Arno Tilles, Mehmet Toner, Martin Yarmush, Application of Micropatterning Techniques to Co-Culture Systems for Hepatic Tissue Engineering, 2005 Annual Meeting of AIChE, Bioengineering Division, Cincinnati, OH, November, 2005
  • Cheul H. Cho, Francois Berthiaume, Arno Tilles, Martin Yarmush, Stimulation of adult rat hepatocyte proliferation in hepatocyte/3T3 fibroblast co-cultures, 2005 Annual Meeting of Biomedical Engineering Society (BMES), Tissue Engineering Session, Baltimore, MD, September, 2005
  • Cheul H. Cho, Jae S. Park, Francois Berthiaume, Arno Tilles, Mehmet Toner, Martin Yarmush, Oxygen consumption rates and liver-specific functions of hepatocyte/fibroblast co-cultures, 2005 Annual Meeting of Biomedical Engineering Society (BMES), Baltimore, MD, September, 2005
  • Cheul H. Cho, Jae S. Park, Francois Berthiaume, Arno Tilles, Mehmet Toner, Martin Yarmush, Oxygen consumption characteristics and liver specific functions of hepatocyte and fibroblast co-culture for bioartificial liver support design, 2005 Annual Meeting of American Chemical Society (ACS), Tissue Engineering Session, San Diego, CA, March, 2005
  • Cheul H. Cho, James F. Eliason and Howard WT Matthew, Porous Glycosaminoglycan-Based Scaffolds for Expansion of Hematopoietic Stem Cells in Perfusion Culture, 2004 World Congress of Biomaterials, Sydney, Australia, 2004
  • Cheul H. Cho, James F. Eliason and Howard WT Matthew, Application of Porous Glycosaminoglycan-Based Scaffolds for Expansion of Hematopoietic Stem Cells in Perfusion Culture, 2003 Annual Meeting of AIChE, Biomaterials Session, San Francisco, CA, November, 2003
  • Cheul H. Cho, James F. Eliason and Howard WT Matthew, In Vitro Expansion of CD34+ Cord Blood Stem Cells on Immobilized Glycosaminoglycans: Effects of Immobilized Method and Stem Cell Purity, 2002 Annual Meeting of AIChE, Bioengineering division, Indianapolis, IN, 2002
  • Cheul H. Cho and Howard WT Matthew, Ionic and Covalent Immobilization of Glycosaminoglycans on Chitosan Surfaces on the Expansion of CD34+ Blood Stem Cells, 2001 Annual Meeting of AIChE, Bioengineering division, Reno, Nevada, 2001
  • Cheul H. Cho, Sundararajan V. Madihally and Howard WT Matthew, Porous Chitosan-Glycosaminoglycan Microcarriers for Hematopoietic Perfusion Cultures: Optimization of Pore Microstructure, 1999 Annual Meeting of AIChE, Bioengineering division, Dallas, TX, 1999
  • J.B. Choi, C.H. Cho, Y.K. Cho, K. Choi, T.S. Lee, Static and Dynamic Analysis of the Tibial Components in Total Knee System, 3rd World Congress of Biomechanics, Sapporo, Japan, 1998