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Department of Biomedical Engineering

Lee, Eun Jung

Contact Info
Title: Assistant Professor
Email: eunjung.lee@njit.edu
Office: 615 Fenster Hall
Phone: 973-596-8471
Dept: Biomedical Engineering
Webpage:

Academic Interests: biomedical engineering

About Prof. Lee



Education

 

Columbia University, Ph.D in Biomedical Engineering (2007)
Columbia University, MS in Biomedical Engineering (2002)

Professional Experience

 

Assistant Professor, New Jersey Institute of Technology, Newark, NJ, July 2011-present
Associate Research Scientist, Yale University, New Haven, CT 2009-2011
Postdoctoral Associate, Yale University, New Haven, CT 2007-2009
Graduate Assistant, Columbia University, New York, NY, 2001-2007

Honors and Awards

 

2005        Late-Breaking Basic Science Abstract at American Heart Association Scientific Sessions2003        Biomedical Engineering Society Graduate Student Research Award

Professional Activities/Organizations

 

SOCIETY MEMBERSHIP
Biomedical Engineering Society, member
American Heart Association, member
New York Academy of Science, member
 
JOURNAL REVIEWER
Biophysical Journal, Molecular and Cellular Biomechanics, Nature Methods, Tissue Engineering, Circulation Research, Regenerative Medicine, Cardiovascular Pathology, Cells Tissues Organs, Journal of Tissue Engineering and Regenerative Medicine

Courses Taught



Cardiovascular Tissue Engineering, Graduate level course, BME698, 3 credits, Fall 2011
Mechanical Fundamentals of Biomedical Engineering, BME301, 3 credits, Spring 2012

Research Activities



Maturation of human embryonic stem cell-derived cardiomyocytes in vitro using 3D engineered
tissue model systems, CT Stem Cell Research Grant (Highest Score)

Publications

 

Maidhof R, Tandon N, Lee EJ, Luo J, Duan Y, Yeager K, Konofagou E,Vunjak-Novakovic G. “Biomimetic perfusion and electrical stimulation applied in concert improved the assembly of engineered cardiac tissue”, Journal of Tissue Engineering and Regenerative Medicine, Dec 13. doi: 10.1002/term.525[Epub ahead of print], 2011. PMID: 22170772.
 
Petersen TH, Calle EA, Zhao L, Lee EJ, Gui L, Raredon, Gavrilov K, Yi T, Zhuang ZW, Breuer C, Herzog E, Niklason LE. “Tissue-engineered lungs for in vivo implantation”, Science, 329(5991):538-41, 2010.
 
Lee EJ, Niklason LE. A novel flow bioreactor for in vitro microvascularization, Tissue Engineering Part C,16(5): 1191-200,2010.
 
Maidhof R, Marsano A, Lee EJ, Vunjak-Novakovic G. “Perfusion seeding of channeled channeled elastomeric scaffolds with myocytes and endothelial cells for cardiac tissue engineering”, Biotechnology Progress, 26(2):565-72, 2010.
 
Lee EJ, Vunjak-Novakovic G, Wang Y, Niklason LE. “A novel biocompatible endothelial cell delivery system for in vitro tissue engineering”, Cell Transplantation, 18(7):731-743, 2009.
 
Lee EJ, Holmes JW, Costa KD. “Remodeling of engineered tissues in response to altered boundary conditions”, Annals of Biomedical Engineering, 36(8): 1322-1334, 2008.
 
Lee EJ, Kim DE, Azeloglu EU, Costa KD. “Tissue engineering: Creation of a functional cardiac organoid”, Tissue Engineering, 14(2): 215-225, 2008 (accepted with no revision).
 
Kim DE, Lee EJ, Martens TP, Kara R, Chaudhry H, Itescu S, Costa KD. “Engineered cardiac tissues for in vitro assessment of contractile function and repair mechanisms”, Conf Proc IEEE Eng Med Biol Soc 1:1545-7, 2006
 
Costa KD, Lee EJ, Holmes JW. “Creating alignment and anisotropy in engineered heart tissue: the role of boundary conditions in a model three-dimensional culture
systems”, Tissue Engineering, 9(4): 567-577, 2003 (with cover illustration).

Patents

 

Engineering cardiac tissue chambers as model systems for studying ventricular mechanics. Invention report M06-018 filed Sep. 1, 2005. Provisional patent application 60/721,399 filed Sep. 28.

Invited Talks

 

Lee EJ. In vitro model systems for cardiovascular tissue engineering, Drexel University, Philadelphia, PA, March 15, 2010
Lee EJ. In vitro model systems for cardiovascular tissue engineering, New Jersey Institute of Technology, Newark, NJ, November 20, 2009
Lee EJ, Niklason LE. Preliminary study of microvascularization using a novel flow bioreactor, Yale Vascular Biology and Therapeutics Program Annual Retreat, New Haven, CT, November 15, 2008.
Lee EJ. Structural and functional charaterization of engineered cardiac tissue, Yale University July 6, 2006
Lee EJ. Structural and functional charaterization of engineered cardiac tissue, University of Pennsylvania, June 20, 2006

Abstracts and Conference Presentations

 

Kim DE, Kao E Kang HR, Lee EJ, Costa KD. Global and regional response to cryo-injury in engineered cardiac tissues, BMES Annual Fall Meeting, Pittsburgh, PA, October 7-10, 2009.
Lee EJ, Kim DE, Azeloglu EU, Costa KD. Engineered cardiac organoid chambers for studying ventricular function, injury and repair, Tissue Engineereing International and Regenerative Medicine Society, San Diego, CA, December 7-10, 2008
Kim DE, Lee EJ, Martens TP, Itescu S, Costa KD. Co-culture with mesenchymal precursor cells or cardiac fibroblasts augments contractile function of myocytes in 3-D engineered cardiac tissues, Society of Physical Regulation in Biology and Medicine, Miami, FL, January 9-11, 2008.
Kim DE, Lee EJ, Costa KD. A soft lithography device for long-term monitoring of contractile force in engineered cardiac tissues, BMES Annual Fall Meeting, Chicago, IL, October 11-14, 2006.
Kim DE, Lee EJ, Martens TP, Kara R, Chaudhry H, Itescu S, Costa KD. Engineered cardiac tissues for in vitro assessment of contractile function and repair mechanisms, The 28th Annual International Conference IEEE Engineering in Medicine and Biology Society, New York, NY, August 31-September 3, 2006.
Lee EJ, Martens TP, Kim DE, Naseem TM, Itescu S, Costa KD. 3-D Engineered tissue model system for characterization of human mesenchymal stem cells with cardiomyocytes in co-culture, World Congress on Medical Physics and Biomedical Engineering, Seoul, Korea, August 27-September 1, 2006.
Lee EJ, Kim DE, Costa KD. Regional mechanics in an engineered tissue chamber model of myocardial infarction, Fifth World Congress of Biomechanics, Munich, Germany, July 29-August 4, 2006.
Lee EJ, Kim DE, Azeloglu EU, Costa KD. Engineered cardiac organoid: Developing a functional biologic micro-pump, The second International Conference on Cell Therapy for Cardiovascular Diseases, New York, NY, January 19-21, 2006.
Lee EJ, Kim DE, Azeloglu EU, Alexander C, Costa KD. Engineered cardiac tissue chambers demonstrate functional Frank-Starling mechanism and positive stroke work, American Heart Association Scientific Sessions, Dallas, TX, November 12-16, 2005 (Late-Breaking Basic Science Abstract).
Lee EJ, Kim DE, Azeloglu EU, Alexander C, Costa KD. Engineered cardiac tissue chambers as model systems for studying ventricular mechanics, BMES Annual Fall Meeting, Baltimore, MD, September 28-October 1, 2005.
Lee EJ, Kim DE, Alexander C, Costa KD. Pressure-volume and stress-strain relationships in engineered cardiac tissue chambers, ASME Annual Summer Conference, Vail, CO, June 22-26, 2005.
Costa KD and Lee EJ. Guiding cardiac tissue architecture by in vitro mechanical stimulation. Whitaker Biomedical Engineering Research Conference, San Diego, CA, August 13-15, 2004.
Kelly TN, Ng KW, Lee EJ, Lima E, Statman LY, Doty SB, Costa KD, Ateshian GA, Hung CT. Development of radial properties of engineered articular cartilage using unconfined compression loading. Trans 50th Annual Meeting of the ORS, San Francisco, CA, March 6-9, 2004.
Lee EJ, Holmes JW, Costa KD. Biaxial material properties of ribose treated collagen gels. BMES Annual Fall Meeting, Nashville, TN, October 1-4, 2003.
Lee EJ, Holmes JW, Costa KD.  Remodeling of engineered tissues in response to altered boundary conditions. BMES Annual Fall Meeting, Nashville, TN, October 1-4, 2003 (BMES Graduate Student Award).
Lee EJ, Knezevic V, Holmes JW, Costa KD. Engineered tissues as model systems for studying myocardial biomechanics. Fourth World Congress of Biomechanics, Calgary, Canada, August 5-9, 2002.
Lee EJ, Costa KD. Boundary conditions determine fibroblast alignment in collagen gels. BMES Annual Fall Meeting, Durham, NC, October 4-7, Annals of Biomedical Engineering, 29:S-43-2001